Predominance of multidrug-resistant Salmonella Typhi genotype 4.3.1 with low-level ciprofloxacin resistance in Zanzibar.
BackgroundTyphoid fever is a common cause of febrile illness in low- and middle-income countries.While multidrug-resistant (MDR) Salmonella Typhi (S.Typhi) has spread globally, fluoroquinolone resistance has mainly affected Asia.MethodsConsecutively, 1038 blood cultures were obtained from patients of all age groups with fever and/or suspicion of se